PM6-D3H4X includes corrections to the halogen-oxygen and halogen-nitrogen interactions, as described in Brahmkshatriya, P. S.; Dobes, P.; Fanfrlik, J.; Rezac, J.; Paruch, K.; Bronowska, A.; Lepsik, M.; Hobza, P. "Quantum Mechanical Scoring: Structural and Energetic Insights into Cyclin-Dependent Kinase 2 Inhibition by Pyrazolo[1,5-a]pyrimidines" Curr. Comput.-Aid. Drug. 2013, 9 (1), 118-129. The accuracy of this method can be seen in Errors in Intermolecular Interaction Energies for X40 set.